Kedvesné dr. Kupai Krisztina: Emergent role of antioxidant enzymes and gasotransmitters in the myocardium
- Emergent role of antioxidant enzymes and gasotransmitters in the myocardium
- Introduction
- Free radicals
- Reactive Oxygen Species
- Cardiac sources of ROS
- Antioxidant protection system
- Heme-oxygenase enzyme (HO)
- Regulation of Heme Oxygenase-1 in cardiovascular diseases
- HO-1 and Myocardial Infarction
- HO-1 and Vascular Occlusion
- Role of CO in the Carotid Body in Heart Failure
- Heme Oxygenase-1 and Preconditioning
- Heme oxygenase improves cardiac function by decreasing oxidative stress
- Link between HO/NOS system and physical exercise
- Heme oxygenase and diabetic heart
- NADPH oxidases
- NADPH oxidase isoforms
- NADPH oxidase in the heart
- NADPH oxidase in diabetic heart
- Role of NADPH oxidases during myocardial ischemia-reperfusion
- NADPH oxidase and exercise
- Nitric oxide synthesizing NOS enzymes
- The NOS-catalyzed reaction
- The NO synthase dimer
- Complexities of coupling NOS pathways in the heart
- Endothelial protection and signaling
- Role of NO in the Carotid Body in Heart Failure
- NOS and cardiac ischemic preconditioning
- Role of Nitric Oxide Signaling Pathway in the Cytosolic and Mitochondrial Signaling of IPC
- eNOS and iNOS knockout mice
- Hypoxia‐ inducible factor 1 α
- Hypoxia inducible factor 1 α as a mediator of ischemic preconditioning
- Hypoxia‐ inducible factor 1 α as a mediator of delayed ischemic preconditioning
- Hypoxia‐ inducible factor 1 α as a mediator of acute cardioprotection
- Role of exercise in the heart
- Gasotransmitters (NO, CO, CH4, H2S)
- Gasotransmitters and Myocardial Ischemia-Reperfusion Injury
- Nitric oxide
- Carbon monoxide
- Methane
- Effects of methane in cardiovascular system
- Hydrogen sulfide
- Biosynthesis and metabolism of H2S
- Physiological role of H2S in cardiovascular system
- Roles of H2S in cardiovascular diseases
- References
- Cardiac Disorders Practice Questions